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doi: 10.1016/j.molliq.2021.116385 174 Kiselova-KanevaYGalunskaBNikolovaMDinchevaIBadjakovI
The color coding system makes it much harder to accidentally inject the wrong dose, which is especially important for people titrating up through the dose schedule
By the studys end, people who stayed on the highest dose lost an average of 28.4% of their baseline weight, amounting to 71 pounds, while those on the lower dose lost an average of 26.4% body weight (the placebo group lost an average of 2.1%)
Consequently, use of treatment policy estimands was not considered appropriate for the base case analyses, and trial product estimands were used in the base case
Additionally, patients may experience increased thyroid hormone levels , which necessitate careful dose adjustments to maintain ideal thyroid function
Future Developments: Higher Dose Tablets In addition to the approved tablet strengths, Novo Nordisk has filed a supplemental drug application for a 25 mg Ozempic tablet for adults with type 2 diabetes
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